A Simple Key For cees dekker Unveiled

‘Yes, that is certainly about ideal. I seek out a Actual physical knowledge of Organic units within a base-up way. I do think you may distinguish 3 strains of study in my group at this time. The primary fears chromosome structure: How would you receive a metre-long DNA polymer folded and organised in such a microscopic cell? We have now developed visualisation strategies that let us to check how, for instance, SMC proteins loop DNA (video clip on Youtube) so as to Establish up chromosomes.

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‘It was simply just a make any difference of finding up a e-book on cell biology and beginning to go through. I had originate from a entire world of ultra-superior vacuums, cryostats and quantum phenomena, and now I used to be Performing at area temperature with molecular biology kits.

Non-equilibrium folding of specific DNA molecules recaptured approximately a thousand instances in the strong state nanopore

2010, produced a fresh way (‘wedging transfer’) to manipulate nanostructures; 1st report of DNA translocation by way of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into reliable-condition nanopores

Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

We use nanofabricated microfluidic structures to sample spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks and this evaluate the fundamental job of spatial confinement for the molecular and cellular amount. Our assignments consist of the subsequent:

Dynamic ParB–DNA interactions initiate and retain a partition condensate for bacterial chromosome segregation

In 1993, for a young and eager associate professor at Delft College of Technological know-how, I had originally centered the investigate attempts of my team on measuring the electrical conductance of only one conducting-polymer molecule. Within two a long time, we experienced established a tool by which an individual wire of a phthalocyaninepolysiloxane polymer was linked concerning two intently spaced metal nanoelectrodes.

Presently, we also recognized that it should be achievable to utilize one semiconducting carbon nanotube to generate a transistor — and we set out to really make it. We stretched personal semiconducting nanotubes throughout metallic electrodes and utilised the underlying silicon substrate for a gate electrode, setting up the basic 3-terminal layout of the area-outcome transistor (Fig.

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Cees Dekker is Distinguished College Professor at TU Delft. Skilled to be a physicist, he pioneered nanotechnology with a lot of discoveries on carbon nanotubes within the nineteen nineties. Given that 2000, he moved to one-molecule biophysics and nanobiology. His recent analysis concentrates on (i) nanopores for protein sequencing; (ii) chromosome construction, especially SMC ceesdekker.net motor protein; and (iii) creating a residing artificial mobile from lifeless molecules. Dekker can be an elected member of the KNAW and fellow towards the APS plus the IOP.

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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent design and style in 2005. (nl)