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2009, discovery of a new phenotype for micro organism in slender nanofluidic slits; and to start with detection of local protein structures together DNA applying reliable-condition nanopores

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, Groningen researchers current the outcome of their initiatives for making labs extra sustainable and supply tips for other labs. 

2007, initially real-time detection of strand exchange in homologous recombination by RecA; discovery of the low persistence size of finishes of microtubules; and resolved the mechanism of biosensing with carbon nanotubes

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Immediate immobilization of native yeast iso-one cytochrome c on bare gold: quickly electron relay to redox enzymes and zeptomole protein-movie voltammetry

All parameters were the identical for each panel In this particular online video, aside from the initial placement from the 6hb rod (proven in blue) within the nanopore. Simulations that terminated early due to translocation of the rod with the pore are marked by a grey track record.

2011, 1st in vitro measurements of transport across a single biomimetic nuclear pore complex; enhancement of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination

2003, demonstrated the initial biosensors produced out of a carbon nanotube; resolved the composition and system of DNA fix proteins; and discovery of a fresh method for fabricating solid-point out nanopores for DNA translocation

one). The current–voltage curves confirmed substantial modulations with gate voltage, even at place temperature, which was in step with band bending inside of a ~0.6 eV bandgap semiconducting nanotube. These facts also showed the conductance could be modulated by six orders of magnitude by switching the gate voltage. The outcome of the function — a place-temperature transistor produced from one carbon nanotube molecule — were revealed in Mother nature in Might 1998.

Testing pseudotopological and nontopological types for SMC-pushed DNA loop extrusion towards roadblock-traversal experiments

Mother nature Physics thanks the nameless reviewers for his or her contribution towards the peer evaluate of the function.

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It had been a very exciting time, all through which I obtained many support from Delft University of Technological innovation, wherever I had been a professor at the time, and I started off quite a few collaborations with molecular biologists. That helped me find out quite a bit.’